Serum β-Carotene Concentrations and the Risk of Congestive Heart Failure in Men: A Population-Based Study

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Background: Congestive heart failure is a major and increasing public health problem in the Western world. Age-associated changes that lead to substantial alterations in the shape and volume of the heart and progressive dilatation and weakening of pump function have been attributed to the long-term cumulative effect of free radicals and reactive oxygen and nitrogen … Read more

Oral Amino Acid Supplements Improve Exercise Capacities in Elderly Patients with Chronic Heart Failure

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This randomized, double-blind, placebo-controlled study investigated whether 30 days of oral supplementation with a special mixture of amino acids (2 packets of amino acids per day for a total of 8 grams per day), could improve exercise capacity as well as post-exercise recovery of a group of 95 elderly outpatients with congestive heart failure. Table … Read more

Low Sodium Versus Normal Sodium Diets in Systolic Heart Failure: Systematic Review and Meta-Analysis

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There is an abundance of scientific evidence to suggest that high dietary salt intake is an important risk factor for cardiovascular and renal morbidity and mortality including stroke, hypertension, myocardial infarction, and renal insufficiency.2-5 Meta-analysis was performed in six clinical studies that were identified using a literature search of several clinical databases in order to … Read more

Low Serum Total Cholesterol Level is a Surrogate Marker, But Not a Risk Factor, for Poor Outcome in Patients Hospitalized With Acute Heart Failure: A Report From the Korean Heart Failure Registry

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While the health risks of hypercholesterolemia are well recognized (i.e. increased risk of coronary heart disease, stroke, Alzheimer’s disease, and all-cause mortality),2-5 the nature and implications of low blood cholesterol are less well understood. Low concentrations of total cholesterol and LDL cholesterol have been associated with an increased risk of cancer (gastrointestinal cancer, hematological cancer, … Read more

Circulating Long-Chain Omega-3 Fatty Acids and Incidence of Congestive Heart Failure in Older Adults: the Cardiovascular Health Study

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The aim of this prospective observational study was to investigate the association, if any, of plasma phospholipid levels of long-chain omega-3 fatty acids, including eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA) with incident congestive heart failure (CHF) in a cohort of 2,735 ambulatory, free-living adults ≥ 65 years of age. Participants in … Read more

Chocolate, Well-Being and Health Among Elderly Men

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A growing number of clinical studies have shown that the regular consumption of flavanol-rich cocoa products is inversely associated with coronary artery disease incidence and mortality. Beneficial physiological effects linked to cocoa and chocolate include: high antioxidant activity, vascular vasodilation, blood pressure reduction, inhibition of platelet activation and aggregation, and decreased inflammation.2-4 Recently, it has … Read more

Body Mass Index and 25 Hydroxyvitamin D Status in Patients With and Without Heart Failure

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Recent clinical research suggests that the biological implications of vitamin D deficiency extend far beyond the control of calcium metabolism. Evidence is accumulating that low vitamin D levels are associated with a number of cardiovascular diseases, including stroke, myocardial infarction, hypertension, and heart failure.2 In this pilot study, researchers from Case Western Reserve University in … Read more